Addiction is a complex and multifaceted condition that impacts individuals and their families on multiple levels. While the stereotypical image of addiction might involve a person misusing substances like alcohol or drugs, addictive behaviours extend beyond substances and include activities such as gambling, internet use, and even food consumption. Understanding addiction requires a comprehensive approach that considers biological, psychological, and social factors—known collectively as the biopsychosocial model (Masiak, 2013). This model provides a holistic framework for exploring the causes, progression, and treatment of addiction.
Biological Factors in Addiction
Genetic Predisposition
Research consistently shows that genetics play a significant role in the development of addictive behaviors (Deak & Johnson, 2021). Individuals with a family history of addiction are at higher risk of developing similar problems. Studies suggest that genetic factors can account for a substantial portion of a person’s vulnerability to addiction (Koob et al., 2023). These inherited traits can influence how the brain responds to substances or addictive activities, making some individuals more susceptible.
For example, variations in genes related to the dopamine system—such as the dopamine receptor D2 gene (DRD2)—can affect the brain’s reward system (Deak & Johnson, 2021). Dopamine, often referred to as the "feel-good" neurotransmitter, plays a central role in reinforcing behaviors. When dopamine release is triggered by a substance or behavior, it creates feelings of pleasure and reward, reinforcing the likelihood of repeating the behavior.
Neurobiology of Addiction
Addiction is often described as a brain disease because it alters the brain's structure and function (Koob et al., 2023). The repeated use of addictive substances or engagement in addictive behaviors hijacks the brain’s reward circuitry, primarily in regions such as the nucleus accumbens and the prefrontal cortex. Over time, the brain becomes dependent on the substance or behavior to maintain normal functioning, leading to tolerance (needing more of the substance to achieve the same effect) and withdrawal symptoms when the substance is removed.
Additionally, chronic use can impair the prefrontal cortex, the area responsible for decision-making, impulse control, and self-regulation (Koob et al., 2023). This impairment makes it difficult for individuals to stop using substances or engaging in addictive behaviors, even when they recognize the negative consequences.
Psychological Factors in Addiction
Trauma and Emotional Regulation
Many individuals struggling with addiction have a history of trauma or adverse childhood experiences (ACEs), such as physical or emotional abuse, neglect, or the loss of a loved one (Hays-Grudo et al., 2021). These experiences can create deep psychological wounds that make it difficult for individuals to manage stress and regulate their emotions.
Substances and addictive behaviors often serve as maladaptive coping mechanisms, providing temporary relief from emotional pain, anxiety, or depression (Mack, 2023). For example, alcohol may be used to numb feelings of sadness, while compulsive internet use may serve as a distraction from feelings of loneliness or inadequacy.
Cognitive Distortions and Beliefs
Cognitive distortions—irrational or exaggerated thought patterns—also contribute to the development and maintenance of addiction (Rezaeisharif et al., 2021). Shapiro (2021) provide some common distortions:
- All-or-Nothing Thinking: "If I can't quit entirely, there's no point in trying."
- Catastrophizing: "If I don’t drink, I won’t be able to handle the stress of my job."
- Minimization: "My drinking isn’t as bad as others, so it’s not a problem."
These distorted beliefs can perpetuate addictive behaviors by justifying continued use or creating a sense of helplessness in the face of attempts to quit (Rezaeisharif et al., 2021).
Social Factors in Addiction
Environmental and Peer Influences
The environment in which a person lives plays a crucial role in shaping their risk for addiction. Factors such as socioeconomic status, availability of substances, and exposure to peer groups that normalize substance use can increase vulnerability (Onyenwe & Odilibe, 2024). Adolescents and young adults, in particular, are highly susceptible to peer influence. Being surrounded by friends or family members who engage in substance use can increase the likelihood of initiating and maintaining addictive behaviors.
Family Dynamics and Support Systems
Family relationships can either contribute to or protect against addiction. Dysfunctional family environments characterized by conflict, neglect, or abuse can increase the risk of addiction (Onyenwe & Odilbe, 2024). On the other hand, supportive relationships and strong social networks can act as protective factors.
Families also play a critical role in the recovery process (Onyenwe & Odilbe, 2024). Family-based therapy, such as multidimensional family therapy (MDFT), has been shown to be effective in treating adolescent substance use disorders by addressing communication patterns, family roles, and relational dynamics that contribute to addiction (Liddle et al., 2023).
The Biopsychosocial Approach to Treatment
Effective addiction treatment recognizes the need to address biological, psychological, and social factors simultaneously. Some common interventions include:
- Biological Interventions:
- Medications for opioid addiction and alcohol dependence can help manage withdrawal symptoms and reduce cravings (Torres-Lockhart et al., 2022).
- Nutritional support and exercise programs can help restore physical health and rebalance brain chemistry (Rosson et al., 2022).
- Psychological Interventions:
- Cognitive Behavioral Therapy (CBT) helps individuals identify and challenge cognitive distortions and develop healthier coping mechanisms (Shapiro, 2019).
- Trauma-focused therapies, such as Eye Movement Desensitization and Reprocessing (EMDR), can address underlying traumatic experiences that contribute to addiction (Martínez-Fernández et al., 2024).
- Social Interventions:
- Support groups such as Alcoholics Anonymous (AA) or Narcotics Anonymous (NA) provide a sense of community and shared experience, reducing the isolation often associated with addiction.
- Family therapy and community-based interventions can strengthen social support networks and promote long-term recovery (Hafford-Letchfield et al., 2020).
Conclusion
Addiction is not a one-dimensional problem but a complex interplay of biological, psychological, and social factors. The biopsychosocial model provides a holistic framework for understanding and addressing addiction, emphasizing the need for comprehensive and individualized treatment. By addressing the underlying causes of addiction and fostering resilience in all areas of life, individuals can achieve lasting recovery and rebuild a life of health, purpose, and connection.
References
Onyenwe, C. A., & Odilibe, I. P. (2024). Socioeconomic determinants of mental health and substance use: A review and Conceptual Solutions for Public Health policy. International Journal of Applied Research in Social Sciences, 6(3), 409–420. https://doi.org/10.51594/ijarss.v6i3.966
Deak, J. D., & Johnson, E. C. (2021). Genetics of Substance Use Disorders: A Review. Psychological Medicine, 51(13), 2189–2200. https://doi.org/10.1017/s0033291721000969
Hafford-Letchfield, T., McQuarrie, T., Clancy, C., Thom, B., & Jain, B. (2020). Community based interventions for problematic substance use in later life: A systematic review of evaluated studies and their outcomes. International Journal of Environmental Research and Public Health, 17(21), 7994. https://doi.org/10.3390/ijerph17217994
Hays-Grudo, J., Morris, A. S., Ratliff, E. L., & Croff, J. M. (2021). Adverse childhood experiences and addiction. Emerging Issues in Family and Individual Resilience, 91–108. https://doi.org/10.1007/978-3-030-56958-7_5
Koob, G. F., Kandel, D. B., Baler, R. D., & Volkow, N. D. (2023). Neurobiology of addiction. Tasman’s Psychiatry, 1–51. https://doi.org/10.1007/978-3-030-42825-9_29-1
Liddle, H. A., Dakof, G., Rowe, C., Mohamed, A. B., Henderson, C., Foulkrod, T., Lucas, M., & DiFrancesco, M. (2023). Multidimensional family therapy for justice-involved young adults with substance use disorders. The Journal of Behavioral Health Services & Research, 51(2), 250–263. https://doi.org/10.1007/s11414-023-09852-5
Mack, W. (2023). Exploration of Coping Strategies in People With a History of Substance Abuse (Order No. 30691045). Available from ProQuest Dissertations & Theses Global. (2878648248). https://www.proquest.com/dissertations-theses/exploration-coping-strategies-people-with-history/docview/2878648248/se-2
Martínez-Fernández, D. E., Fernández-Quezada, D., Garzón-Partida, A. P., Aguilar-García, I. G., García-Estrada, J., & Luquin, S. (2024). The effect of eye movement desensitization and reprocessing (EMDR) therapy on reducing craving in populations with substance use disorder: A meta-analysis. Brain Sciences, 14(11), 1110. https://doi.org/10.3390/brainsci14111110
Masiak, J. (2013). Biopsychosocial model of addictions and other approaches. Zdrowie Publiczne, 123(4), 321-324. https://doi.org/10.12923/j.0044-2011/123-4/a.12
Rezaeisharif, A., Karimi, A., & Naeim, M. (2021). Effectiveness of the cognitive restructuring approach on irrational beliefs and hopelessness in individuals with a substance abuse disorder: A randomized controlled trial. Addictive Disorders & Their Treatment, 20(4), 326–335. https://doi.org/10.1097/adt.0000000000000264
Rosson, S., de Filippis, R., Croatto, G., Collantoni, E., Pallottino, S., Guinart, D., Brunoni, A. R., Dell’Osso, B., Pigato, G., Hyde, J., Brandt, V., Cortese, S., Fiedorowicz, J. G., Petrides, G., Correll, C. U., & Solmi, M. (2022). Brain stimulation and other biological non-pharmacological interventions in mental disorders: An umbrella review. Neuroscience & Biobehavioral Reviews, 139, 104743. https://doi.org/10.1016/j.neubiorev.2022.104743
Shapiro, L. (2019). Cognitive behavioral therapy: Worksheets: 65+ ready-to-use CBT worksheets to motivate change, practice new behaviors and regulate emotion. PESI.
Torres‐Lockhart, K. E., Lu, T. Y., Weimer, M. B., Stein, M. R., & Cunningham, C. O. (2022). Clinical management of opioid withdrawal. Addiction, 117(9), 2540–2550. https://doi.org/10.1111/add.15818